We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......


Lewis C. Mills, M.D.; B. F. Boylston, M.D.; James A. Greene, M.D.; John H. Moyer, M.D.
JAMA. 1957;164(12):1310-1314. doi:10.1001/jama.1957.02980120014004.
Text Size: A A A
Published online


• Septic arthritis developed in two patients while they were on steroid therapy. One, a woman aged 34, had received corticotropin, cortisone, hydrocortisone, and prednisone at various times over a period of years in the treatment of lupus erythematosus. The severe, destructive septic arthritis that developed about the left knee was remarkable because of the absence of pain and fever. It was successfully treated with chloramphenicol and streptomycin. The other patient, a man aged 54, had a recurrent generalized exfoliative dermatitis treated at various times with prednisone, corticotropin, and hydrocortisone. The septic arthritis that developed in this patient involved one knee and both hands and resulted in complete dislocation of the left index finger; it was likewise characterized by comparative freedom from either pain or fever. It is very difficult in such cases to distinguish a developing septic arthritis from a preexisting arthritis for which the patient is being treated. A diagnostic aspiration of material from the affected joints should be done early.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.