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ARTICLE |

TOXICITY OF ARSENIC AS USED IN TREATMENT OF ASTHMA

Louis Pelner, M.D.; Samuel Waldman, M.D.
JAMA. 1952;150(15):1511-1512. doi:10.1001/jama.1952.03680150065028.
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ABSTRACT

To the Editor:  —In The Journal, Oct. 11, 1952, are two articles that mention the dangers of the treatment of asthma with inorganic arsenicals (Unger and Unger, page 562, and Silver and Wainman, page 584). In both articles mention is made of a case report in The Journal by Pascher and Wolf (March 1, 1952, page 734). All three of these articles fail to take notice of a communication by us in the New York State Journal of Medicine for Nov. 1, 1951, in which a case is described, a review of the literature is given, and the possible method of action of arsenic in chronic asthma is postulated. Another patient showing arsenic poisoning involving the liver, skin, and peripheral nerves has come under our care, and a patient treated by one of our colleagues had similar toxic effects. We have also heard of a case in which toxic encephalopathy

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