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MYCOTIC ANEURYSM OF THE CIRCLE OF WILLIS

T. K. Rathmell, M.D.; George Mora, M.D.; Johannes F. Pessel, M.D.
JAMA. 1952;150(6):555-556. doi:10.1001/jama.1952.03680060027008.
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In the Gulstonian Lectures of 1885, Sir William Osler1 stated, "The meningeal complication of endocarditis has not received much attention." Osler's remark is as revealing today as it was then.

We shall review a case of subacute bacterial endocarditis in which a mycotic aneurysm of the right middle cerebral artery was discovered at autopsy. This lesion of the intracranial vessels has been noted in only 34 previous cases.2 A brief review of the pathological changes of mycotic aneurysm of the circle of Willis will be given. In the present period of antibiotic therapy, studying a case of this type constitutes a rare pathological experience.

REPORT OF A CASE  An unmarried white woman, 50, was admitted in a comatose condition with a left hemiplegia of six days' duration. She was known to have recently had a blood transfusion and to have had severe anemia for over two years. Liver

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