Werner Knapp, M.D.
JAMA. 1954;156(2):195. doi:10.1001/jama.1954.02950020101029.
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To the Editor:—  In two reports published in 1953 (Deutsche med. Wchnschr.78:532-535 [April 10] 1953; Virchows Archiv für pathologische Anatomie323:664-684, 1953), Masshoff described the frequent occurrence of a benign, abscess-forming mesenterial lymphadenitis in adolescents which, causing symptoms suggestive of those of acute appendicitis, often led to surgical intervention. At operation the presence of an abundant and clear peritoneal exudate was noted. Usually the appendix appeared normal, but enlarged lymph nodes were found to be present singly or in groups in the mesenterium, particularly in the ileocecal region. In a small number of cases signs of acute gastroenteritis dominated the clinical picture. Laboratory studies of the cause of this new syndrome gave the following results:1. In 3 of the 15 cases in which the presence of the above described lymphadenitis had been proved histologically, Pasturella pseudotuberculosis could be isolated from operatively removed lymph nodes. 2. The


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