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William S. Schwartz, M.D.
JAMA. 1952;148(8):600-602. doi:10.1001/jama.1952.02930080010003.
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At present, there are a number of effective drugs available for the treatment of many of the common acute pulmonary infections; for example, Pneumococcus pneumonia can be controlled successfully by sulfadiazine, penicillin, aureomycin, chloramphenicol, or terramycin. It is desirable in many cases of pneumonia and in other types of pulmonary infection to determine the exact etiological agent and its sensitivity to the various antibiotics before beginning treatment. Unfortunately, this is frequently impossible because the patient's condition requires immediate therapy or laboratory facilities to perform the tests are lacking. Most hospitalized patients suffering from pneumonia now receive penicillin because of its low toxicity and low cost; however, in most cases, the advantage of oral administration is so great that any one of the three latter antibiotics are likely to become even more popular than they now are, if their cost is reduced. Since aureomycin, chloramphenicol, and terramycin have a broad antibacterial


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