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JAMA. 1951;147(10):979. doi:10.1001/jama.1951.03670270069018.
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Selzer and his associates1 attempted to evaluate the photofluorographic tuberculosis mass survey as a means of detecting unknown heart disease. The study was conducted for a period of 31 months by the Heart Division of the San Francisco Tuberculosis Association. Approximately 155,000 minifilms (35 mm.) were taken in search of tuberculosis. The tuberculosis survey film readers were instructed to report, in addition to tuberculosis, any suspected abnormality of the cardiovascular shadow. Abnormal-appearing cardiac shadows were considered to be present in 1,356 (0.87%). Eight hundred forty-six persons with abnormal-appearing shadows were reexamined fluoroscopically, and the presence of abnormal shadows was confirmed in only 514, or 60.7%. It appeared, therefore, that fluoroscopy is of value in eliminating many false-positive minifilms. One hundred ninety-three of the patients with abnormal observations confirmed by fluoroscopic examination were referred to physicians. Twenty-eight of these patients had no evidence of heart disease. Evidence of clinical heart


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