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Maurice J. Small, M.D.
JAMA. 1951;147(10):932-937. doi:10.1001/jama.1951.03670270022009.
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Cortisone therapy of pulmonary sarcoidosis has as yet not been reported in the literature.1 Thorn and his co-workers1a reported one case of sarcoidosis, with pulmonary, uveal, and osseous manifestations, treated with 40 mg. of corticotrophin (ACTH) daily for eight days, without significant clinical or roentgen improvement. The patients reported on below were treated with 100 mg. of cortisone daily for four to six weeks and showed such marked improvement in clinical status, roentgen appearance, and pulmonary function that I consider them worth describing.


Case 1.—History.  —W. K. A., a 28-year-old Negro male veteran, was admitted to Halloran Veterans Administration Hospital on Aug. 14, 1950, with the chief complaints of cough, productive of moderate amounts of clear, mucoid sputum, and substernal pain. He was well until eight months prior to admission, at which time "a cold" developed. In addition to the cough, he experienced at


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