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COUNCIL ON PHARMACY AND CHEMISTRY

JAMA. 1951;147(4):322-325. doi:10.1001/jama.1951.03670210034008.
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Harris, S. A., and Folkers, K.:  Synthetic Vitamin B0 , Science 89: 347, 1939.
Link to Article[[XSLOpenURL/10.1126/science.89.2311.347]]
Gunsalus, I. C.; Umbreit, W. W.; Bellamy, W. D., and Foust, C. E.:  Some Properties of Synthetic Codecarboxylase , J. Biol. Chem. 161:743, 1945.
Lichstein, H. C.; Gunsalus, I. C., and Umbreit, W. W.:  Function of Vitamin B6 Group: Pyridoxal Phosphate (Codecarboxylase) in Transamination , J. Biol. Chem. 161:311, 1945.
György, P. and Eckardt, R. E.:  Vitamin B6 and Skin Lesions in Rats , Nature 144:512, 1939.
Link to Article[[XSLOpenURL/10.1038/144512a0]]
Chick, H.; ElSadr, M. M., and Worden, A. N.:  Occurrence of Fits of an Epileptic Nature in Rats Maintained for a Long Period on a Diet Deprived of Vitamin B6 , Biochem. J. 34:595, 1940.
Daniel, E. P.; Kline, O. L., and Tolle, C. D.:  A Conclusive Syndrome in Young Rats Associated with Pyridoxine Deficiency , J. Nutrition 23: 205, 1942.
Fouts, P. J.; Helmer, O. M.; Lepkovsky, S., and Jukes, T. H.:  Production of Microcytic Hypochromic Anemia in Puppies on Synthetic Diet Deficient in Rat Antidermatitis Factor (Vitamin B6) , J. Nutrition 16:197, 1938.
Wintrobe, M. M.; Follis, R. H.; Miller, M. H.; Stein, H. J.; Akuyaga, R.; Humphreys, S.; Suksta, A., and Cartwright, G. E.:  Pyridoxine Deficiency in Swine: with Particular Reference to Anemia, Epileptiform Convulsions and Fatty Liver , Bull. Johns Hopkins Hosp. 72:1, 1943.
Rinehart, J. F. and Greenberg, L. D.:  Arteriosclerotic Lesions in Pyridoxine-Deficient Monkeys , Am. J. Path. 25:481, 1949.
Greenberg, L. D., and Rinehart, J. F.:  Xanthurenic Acid Excretion in Pyridoxine Deficient Rhesus Monkeys , Federation Proc. 7: 157, 1948.
Reid, D. F.; Lepkovsky, S.; Bonner, D., and Tatum, E. L.:  The Intermediary Metabolism of Tryptophane in Pyridoxine-Deficient Rats , J. Biol. Chem. 155: 299, 1944.
Axelrod, H. E.; Morgan, A. F., and Lepkovsky, S.:  The Fate of Tryptophane in Pyridoxine-Deficient and Normal Dogs , J. Biol. Chem. 160: 155, 1945.
Miller, E. C., and Baumann, C. A.:  Relative Effects of Casein and Tryptophane on the Health and Xanthurenic Excretion of Pyridoxine-Deficient Mice , J. Biol. Chem. 157:551, 1945.
Conger, T. W., and Elvehjem, C. A.:  The Biological Estimation of Pyridoxine (Vitamin B6) , J. Biol. Chem. 138: 555, 1941.
Michaud, E. C., and Elvehjem, C. A.:  Nutritional Requirements of the Dog , Nutrition Abstr. & Rev. 13: 323, 1944.
Schweigert, B. S.; Sauberlich, H. E.; Elvehjem, C. A., and Baumann, C. A.:  Dietary Protein and the Vitamin B6 Content of Mouse Tissue , J. Biol. Chem. 165: 187, 1946.
Bird, H. R.:  The Vitamin Requirements of Chicks , Vitamins and Hormones 5: 163, 1947.
Spies, T. D.; Bean, W. B., and Ashe, W. F.:  A Note on the Use of Vitamin B6 in Human Nutrition , J. A. M. A. 112:2414 ( (June 10) ) 1939.
Spies, T. D.; Ladisch, R. K., and Bean, W. B.:  Vitamin B6 (Pyridoxine) Deficiency in Human Beings , J. A. M. A. 115: 839 ( (Sept. 7) ) 1940.
Antopol, W., and Schotland, C. E.:  Use of Vitamin B6 in Pseudo-Hypertrophic Muscular Dystrophy , J. A. M. A. 114: 1058 ( (March 23) ) 1940.
Ferrebee, J. W.; Klinigman, W. O., and Frantz, A. M.:  Vitamin E and Vitamin B6 Clinical Experience in the Treatment of Muscular Dystrophy and Amyotrophic Lateral Sclerosis , J. A. M. A. 116:1895 ( (April 26) ) 1941.
Link to Article[[XSLOpenURL/10.1001/jama.1941.02820170013005]]
Rosenbaum, E. E.; Portis, S., and Soskin, S.:  Relief of Muscular Weakness by Vitamin Bo , J. Lab. & Clin. Med. 27: 763, 1942.
Eaton, L. M.; Woltman, H. W., and Butt, H. R.:  Vitamin E and B6 in Treatment of Neuromuscular Diseases , Proc. Staff Meet., Mayo Clin. 16: 523, 1941.
Barker, W. H.; Stein, J.; Miller, M. H., and Wintrobe, M. M.:  Failure of Pyridoxine (Vitamin B6) to Modify the Parkinsonian Syndrome , Bull. Johns Hopkins Hosp. 69:266, 1941.
Zeligs, M. A.:  Use of Pyridoxine HCl in Parkinsonism , J. A. M. A. 116:2148 ( (May 10) ) 1941.
Baker, A. B.:  Treatment of Paralysis Agitans with Vitamin B6 (Pyridoxine-HCl) , J. A. M. A. 116:2434 ( (May 31) ) 1941.
Meller, C. L.:  Ten Cases of Paralysis Agitans Treated with Vitamin B6 , Minn. Med. 25:22, 1942.
Wright, C. S.; Samitz, M. H., and Brown, H.:  Vitamin B6 (Pyridoxine) in Dermatology , Arch. Derm. and Syph. 47:651, 1943.
Jolliffe, N.; Rosenblum, L. A., and Sawhill, T.:  The Effects of Pyridoxine (Vitamin B6) on Persistent Adolescent Acne , J. Invest. Dermat. 5:143, 1942.
Chick, H.; Macrae, T. F.; Martin, A. J. P., and Martin, C. J.:  The Water-Soluble B Vitamins Other Than Aneurin (Vitamin B1), Riboflavin, and Nicotinic Acid Required by the Pig , Biochem. J. 32:2207, 1938.
Fox, J. T., and Tullidge, G. M.:  Pyridoxine (Vitamin Bi) in Epilepsy , The Lancet 2:345, 1946.
Smith, P. K.:  Effect of Various Substances on Swing Sickness , Proc. Soc. Exp. Biol. and Med. 63: 209, 1946.
Maxfield, J. R.; Mcllwain, A. J., and Robertson, J. E.:  Treatment of Radiation Sickness with Vitamin B6 (Pyridoxine-HCl) , Radiology 41: 383, 1943.
Shorvon, L. M.:  Pyridoxine in Treatment of Radiation Sickness , Brit. J. Radiol. 19:369, 1946.
Wells, J. J., and Popp, W. C.:  The Use of Pyridoxine-HCl in the Treatment of Radiation Sickness: Preliminary Report , Proc. Staff Meet., Mayo Clin. 22: 482, 1947.
Willis, R. S.; Winn, W. W.; Morris, A. T.; Newsome, A. A., and Massey, W. S.:  Clinical Observations in Treatment of Nausea and Vomiting in Pregnancy with Vitamins B1 and B6: Preliminary Report , Am. J. Obst. & Gynec. 44:265 ( (Aug.) ) 1942.
Weinstein, B. B.; Mitchell, G. J., and Sustendal, G. F.:  Clinical Experiences with Pyridoxine-HCl in Treatment of Nausea and Vomiting in Pregnancy , Am. J. Obst. & Gynec. 46: 283, 1943.
Weinstein, B. B.; Wohl, Z.; Mitchell, G. J., and Sustendal, J. E.:  Oral Administration of Pyridoxine-HCl in Treatment of Nausea and Vomiting of Pregnancy , Am. J. Obst. & Gynec. 47: 389, 1944.
Silbernagel, W. M., and Burt, O. P.:  Effects of Pyridoxine on Nausea and Vomiting of Pregnancy , Ohio State M. J. 39: 1113, 1943.
Hesseltine, H. C.:  Pyridoxine Failure in Nausea and Vomiting of Pregnancy , Am. J. Obst. & Gynec. 51: 82 ( (Jan.) ) 1946.
McGanity, W. J.; McHenry, E. W.; Van Wyck, H. B., and Watt, G. L.:  An Effect of Pyridoxine on Blood Urea in Human Subjects , J. Biol. Chem. 178: 511, 1949.
Hawkins, W. W.; McFarland, M. L., and McHenry, E. W.:  Nitrogen Metabolism in Pyridoxine Insufficiency , J. Biol. Chem. 166:223, 1946.
Umbreit and Gunsalus, in O'Kane, D. E., and Gunsalus, I. C.:  The Resolution and Purification of Glutamic-Aspartic Transminases , J. Biol. Chem. 170:425, 1947.
Hawkins, W. W., and Barsky, J.:  An Experiment on Human Vitamin B6 Deprivation , Science 108:284, 1948.
Link to Article[[XSLOpenURL/10.1126/science.108.2802.284]]
Greenberg, L. D.; Bohr, D. F.; McGrath, H., and Rinehart, J. F.:  Xanthurenic Acid Excretion in the Human Subject on a Pyridoxine-Deficient Diet , Arch. Biochem. 21:237, 1949.
Lepkovsky, S.; Roboz, E., and Haagen-Smith, A. J.:  Xanthurenic Acid and Its Role in the Tryptophane Metabolism of Pyridoxine-Deficient Rats , J. Biol. Chem. 149:195, 1943.
Mueller, J. F., and Vilter, R. W.:  Pyridoxine Deficiency in Human Beings Induced by Desoxypyridoxine , J. Clin. Invest. 29: 193, 1950.
Link to Article[[XSLOpenURL/10.1172/JCI102246]]
Snyderman, S. E.; Carretero, R., and Holt, L. E.:  Pyridoxine Deficiency in the Human Being , Federation Proc. 9:371, 1950.

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