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TREATMENT OF ACNE VULGARIS

George C. Andrews, M.D.; Anthony N. Domonkos, M.D.; Charles F. Post, M.D.
JAMA. 1951;146(12):1107-1113. doi:10.1001/jama.1951.03670120017005.
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Stuart Way and one of us (G. C. A.) recently reviewed the literature of acne vulgaris with especial reference to hormone imbalance.1 The present paper simply describes an experiment. Two years ago we decided to try to use for a year only antibiotics and estrogenic substances in treatment of acne vulgaris and not to employ X-ray irradiation.

We had up to that time achieved some good results with antibiotics, estrogenic substances, and other modern medicines. This small success made us wonder whether modern medical progress had reached a point where acne could be cured by these remedies. Our success during this first year of the experiment was so satisfactory to all that we have continued the experiment through the second year without any misgivings as to its superiority over the older methods of treatment in vogue five or 10 yr. ago.

Whereas prior to the beginning of this experiment

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