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JAMA. 1951;146(7):671-672. doi:10.1001/jama.1951.03670070063024.
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Biopsy During Operation.  —Dr. Ernani T. Torres, head of the department of pathology of the Rio de Janeiro Hospital dos Servidores, published a report on 1,000 successive biopsies performed during operation; 1,258 specimens were examined. In this series, the pathological and clinical diagnoses coincided in 890 cases (89%); in 109 cases (10.9%) the clinical diagnosis was changed by the result of the pathological examination performed during the operation, and in many instances the surgical operation was modified according to the results of biopsy. In only one case was a definite diagnosis not possible. The patient concerned had had jaundice for the previous seven months and, recently, loss of weight, abdominal pain, and dyspnea. There was rigidity of the abdomen and evident guarding over the right hypochondrium. The clinical diagnosis was obstructive jaundice, rupture, or perforation of the biliary ducts. An exploratory laparotomy was performed, with excision of Vater's papilla. The


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