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Chester I. Mead, M.D.
JAMA. 1951;146(2):85-87. doi:10.1001/jama.1951.03670020007003.
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Coccidioidomycosis is a disease which only recently has become important as a diagnostic problem in children in certain sections of the country. The disease was first recognized in Kern County, Calif., in 1901 in its granulomatous form.

For many years a disease entity existed in the Central Valley of California, characterized by fever, cough, malaise and erythema nodosum. In 1935 Dr. Myrnie Gifford1 of the Health Department of Kern County first recognized that the disease entity was due to the fungus Coccidioides immitis. Soon after this Dr. Charles Smith2 of the Department of Health of Stanford University and now head of the School of Public Health at the University of California, in collaboration with the physicians of Kern and Tulare counties,3 did a great amount of research on the so-called "valley fever," piecing together the fragmentary knowledge of this disease. He developed new tests, which have greatly


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