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Victor L. Cohen, M.D.
JAMA. 1951;145(3):174. doi:10.1001/jama.1951.02920210046019.
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To the Editor:—  In regard to the article "Importance of Foods in Patients as Determined by Skin Testing and Intentional Feeding," by Leibowitz, Chester and Markow (J. A. M. A. 144: 990 [Nov. 18] 1950), I feel that in two respects there is a possibility for more precision in the study.

  1. Skin tests must be done in more than one dilution in order to rule out the possibility of a positive cutaneous reaction. This idea was first suggested in Coca, Walzer and Thomman's "Asthma and Hayfever in Theory and Practice" (Springfield, Ill., Charles C Thomas, Publisher, 1931). In the section on atopens and other excitants, the authors state that for intracutaneous testing a solution containing 0.0001 or 0.001 mg. per cubic centimeter may be employed "to start with, depending on the age of the patient and the degree of clinical sensitivity reported in the history. Stronger solution may be


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