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George A. Pipilis, M.D.; Paul H. Wosika, M.D., Ph.D.
JAMA. 1951;145(3):147-152. doi:10.1001/jama.1951.02920210019005.
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Ventricular aneurysm, known since the description of Galeati nearly 200 years ago,1 frequently remains an autopsy finding because of the nonspecific clinical features. Published studies concern a limited number of cases, and only a few have referred to all the improved laboratory methods now available for antemortem diagnosis. This paper reports five cases of ventricular aneurysm, proved pathologically, from the Illinois Masonic Hospital, one of which was diagnosed electrocardiographically because the tracing was characteristic of anterior myocardial infarction with persistent elevation of the RS-T segment over a two year period.

LITERATURE  Aneurysm may result from an abscess of the cardiac wall, trauma, ulcerative lesions of bacterial endocarditis or congenital defects, but nearly all cases are preceded by myocardial infaraction.2 The fibrosis of the healed infarction is weak and dilates because of intraventricular pressure. The time at which the fibrotic wall gives way in the formation of an aneurysmal


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