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VERATRUM VIRIDE IN THE TREATMENT OF ECLAMPSIA: II

RICHARD D. BRYANT, M.D.; JOHN G. FLEMING, M.D.
JAMA. 1940;115(16):1333-1339. doi:10.1001/jama.1940.02810420019006.
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In 1935, one of us1 reported a series of cases of eclampsia treated at the Cincinnati General Hospital during the previous ten years. The use of the vasodilating drug veratrum viride was stressed. Previously this drug had been used with success by Dr. William Gillespie as chief of the obstetric service until his death in 1925. Since then under his successor, Dr. H. L. Woodward, and his attending staff details of the management of eclampsia have been further refined and improved. Since 1930 there have been but minor variations in the treatment. We believe that a sufficient number of cases have been treated successfully to justify the conclusions that veratrum viride is an extremely valuable adjunct in the management of eclampsia and that the drug itself is not a source of danger to the patient (as is stated in a current standard textbook) if used in therapeutic doses.

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