This book was published by the guarantors of the journal Brain, themselves neurologists and physiologists, because they wished to make some of Sherrington's reprints and extracts of his published papers more readily available for those interested in biologic, physiologic and clinical medical sciences. In this excellent compilation one will find the original descriptions of the spinal animal, the experimental isolation of skin and muscle segmentation, observations on reflexes and their interaction, the motor representation in the primate cortex and the fundamental proof of reciprocal innervation and postural reflexes. The conception of central inhibition is also discussed. This book is highly recommended to the neurologist, physiologist and psychologist. It will serve as an excellent reference manual for all of Sherrington's contributions.