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LACK OF EVIDENCE FOR CHRONIC CARBON MONOXIDE POISONING

Yandell Henderson, Ph.D.
JAMA. 1940;115(9):796. doi:10.1001/jama.1940.02810350140025.
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ABSTRACT

To the Editor:—  Whether there really is such a disease as that termed "chronic carbon monoxide poisoning," as a consequence of prolonged or repeated exposure to small amounts of the monoxide and continuing after the exposure is stopped, is very doubtful. Certainly its importance in many cases is less medical than legal and financial as a basis for claims for damages to be awarded by a compensation commissioner or a court of law. There is a large literature presenting numerous cases, described with clinical fulness and accuracy in respect to the symptoms of the disorder but with little or no evidence that the patients had ever been exposed to any significant extent to carbon monoxide.If, then, numerous false claims are not to be bolstered by such papers, it is essential that writers on this subject should be required to report evidence as to the analytic method by which the

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