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CLINICAL USE OF IMMUNE HUMAN PLACENTAL GLOBULIN IN CHICAGO

HERMAN N. BUNDESEN, M.D.; WILLIAM I. FISHBEIN, M.D.; IRVING R. ABRAMS, M.D.; RICHARD D. MILLER, B.M.
JAMA. 1940;115(2):104-107. doi:10.1001/jama.1940.02810280016005.
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In 1938 more cases of measles were reported in Chicago than during any year since this disease was made reportable. Table 1 shows that apparently there has been no reduction in the number of cases of measles reported each year over the last twenty-five years. Rather the trend is toward more cases, probably because of better reporting. The mortality, however, has dropped rather steadily from 12.4 per hundred thousand of population in 1913 to 1.1 in 1938.

It should be noted in table 1 that only the years of largest incidence are charted, one might say the epidemic years. In 1938 the case fatality was amazingly low, being 0.1 per cent, whereas in 1913 it was 1.9 per cent. However, during this year the case fatality was low over the entire country. Improved housing, more adequate medical care, better nursing attention, increased use of measles-modifying substances in susceptible contacts, recent

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