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August 20, 1949, Vol 140, No. 16 >
ARTICLE | August 20, 1949

TWINS WITH PEPTIC ULCERS

A. C. Ivy, M.D.
JAMA. 1949;140(16):1290. doi:10.1001/jama.1949.02900510040018.
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ABSTRACT

To the Editor:—  The study of twins is of great value in providing information concerning the respective importance of hereditary predisposition and environmental influences in disease in man. The results of the use of this method have shown a hereditary predisposition to tuberculosis, diabetes and tumor formation and a high, medium or low intelligence quotient.There is some a priori evidence showing a hereditary predisposition for peptic ulcer. Only 6 cases of the occurrence of peptic ulcer in the one or both of monozygous or dizygous twins have been reported in the readily accessible literature. Since twins are born in 1 of 86 births and identical twins in 1 of 344 births and the general incidence of ulcer is 5 to 10 per cent, there should be plenty of material available.I should like to ask physicians to cooperate in assembling such material by sending me reports of cases in

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