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ARTICLE |

Toxoplasmosis: A Clinical, Serological and Histopathological Study with Special Reference to the Eye Manifestations. Presentation of Twenty Cases of Proved or Presumable Toxoplasmic Retinopathy and Retino-Encephalopathy with Associated Ocular Manifestations

JAMA. 1949;140(13):1132. doi:10.1001/jama.1949.02900480062032.
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ABSTRACT

This monograph on toxoplasmosis covers the field mentioned in the long title. It gives a comprehensive review of the existent knowledge of the subject divided into the usual scheme of epidemiology, immunology, histopathology, clinical aspects, diagnosis and treatment. Sulfonamide compounds have slight therapeutic effect in experimentally infected animals; penicillin has no effect, and streptomycin and chloramphenicol apparently have not yet been tested. There is a brief summary of the 49 cases thus far reported, including 20 of the author's, with detailed discussion of ocular changes.

The serologic studies reported are not reliable, being based on old technic which has since been improved. The clinical and pathologic descriptions and the illustrations are excellent. Here and there are slight deviations from conventional English, indicating foreign authorship, which adds a degree of charm to the opus.

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