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A POST-MYOCARDIAL-INFARCTION SYNDROME PRELIMINARY REPORT OF A COMPLICATION RESEMBLING IDIOPATHIC, RECURRENT, BENIGN PERICARDITIS

William Dressler, M.D.
JAMA. 1956;160(16):1379-1383. doi:10.1001/jama.1956.02960510005002.
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• Myocardial infarction was followed in 10 instances by a febrile complication resembling idiopathic pericarditis with pleuritis and/or pneumonitis. A pericardial friction rub was heard in eight cases. Roentgenologic evidence of pericardial effusion was found in two cases. Pleural effusion occurred in seven.

Associated with the signs of pericarditis was a peculiar temperature curve that showed protracted periods of low-grade fever between high peaks of fever and flare-ups of pain. Leukocytosis, occasionally giving counts as high as 35,000 cells per cubic millimeter, was present in 7 of the 10 cases.

Frequent relapses prolonged the febrile course to weeks or months, but in all cases the outcome was favcrable.

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