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June 11, 1949, Vol 140, No. 6 >
ARTICLE | June 11, 1949

SEXUAL REPRODUCTION IN VIRUSES

JAMA. 1949;140(6):541-542. doi:10.1001/jama.1949.02900410037011.
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Bacterial viruses can enter bacteria, where they reproduce themselves in large numbers; later they are released by rupture of the bacterium and its conversion into a mass of bacteriophage or virus particles.1 Bacteria and the viruses that feed on them have been considered one of the best and simplest systems for study of multiplication of viruses. Discussing the "interference phenomena" in virus diseases, Andrews2 wrote that the existence of one virus in a host often precludes the entrance of a second virus. Such interference phenomena have been demonstrated many times in tissue cultures and with the bacterial viruses. With a variation of this principle, Delbrück and Bailey3 recently uncovered new information about the reproductivity and method of establishment of mutant strains of virus. They worked with viruses T2 and T4r, which are genetically related and can enter and reproduce in the same bacterium of a

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