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JAMA. 1956;160(9):779-780. doi:10.1001/jama.1956.02960440051015.
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In the Federal Register for November 301 is an order signed by John L. Harvey, acting commissioner, Food and Drug Administration, indicating the first permissible use of an antibiotic as a food preservative. Chlortetracycline has been cleared for use in the processing of fresh-killed poultry. In accordance with the legal responsibility of the FDA for the establishment of tolerances, the order states, "A tolerance of seven parts per million is established for residues of chlortetracycline in or on uncooked poultry and this tolerance level should not be exceeded in any part of the poultry." Currently, the normal store life of a chicken carcass approximates seven days. By using chlortetracycline as a food preservative, the store life of a poultry carcass maintained under standard commercial refrigeration will be extended to between 14 and 21 days.

Acronize is the trade-mark for the various formulated products of the special food-grade chlortetracycline with


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