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April 30, 1949, Vol 139, No. 18 >
ARTICLE | April 30, 1949

EVALUATION OF TREATMENT OF HYPERTENSION

WINCHELL McK. CRAIG, M.D.
JAMA. 1949;139(18):1239-1247. doi:10.1001/jama.1949.02900350001001.
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Essential hypertension, similar to all disease entities the causes of which are obscure, has a tendency to progress as time and age advance. It requires careful and frequent observation, and treatment should be instituted before severer stages of the disease develop. Abnormal elevation of the blood pressure may persist for years in a minimal degree without producing symptoms or disability, and severer elevation of blood pressure may respond to medical management and remain under control without proving disabling or showing evidence of progression. The problem confronting the medical profession today is the control of progressive hypertension and the prevention of irreparable damage to the various structures of the body.

Not much is known about the mechanism of elevation of the blood pressure in essential hypertension. Three factors are responsible for maintaining normal blood pressure, and derangement of any one of these may cause a change in the blood pressure. The

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