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ARTICLE |

Oral Vaccines and Immunization by Other Unusual Routes

JAMA. 1949;139(15):1044-1045. doi:10.1001/jama.1949.02900320074036.
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ABSTRACT

This book reviews the literature regarding the experimental and clinical aspects of immunization by way of the mouth, rectum, respiratory tract, skin, vagina and other areas. As stated in the preface, the book was completed in 1936 but because of several misfortunes was not published. Although the literature for 1936 to 1947 was added by Mr. Morrison, it is not as thorough as previous to 1936. Of some thousand references, only 3 per cent are after 1936. Almost 100 pages are devoted to oral vaccination with BCG. The next in order of space allowed were typhoid and bacillary dysentery, vaccination against common colds (using the common organisms found in the nose and throat but not viruses). Of historical interest, oral vaccinations have been tried against smallpox, pneumonia, measles, septic wounds, hay fever, poison ivy, tetanus, snake venom, etc.

The sum of this review is that experimentally in animals and man

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