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TREATMENT OF ACUTE INFECTIOUS HEPATITIS IN THE ARMED FORCES:  ADVANTAGES OF AD LIB. BED REST AND EARLY RECONDITIONING

Thomas C. Chalmers; William E. Reynolds, M.D.; Richard D. Eckhardt; Joaquin G. Cigarroa, M.D.; Norman Deane, M.D.; Robert W. Reifenstein, M.D.; Clifford W. Smith, M.D.; Charles S. Davidson, M.D.
JAMA. 1955;159(15):1431-1434. doi:10.1001/jama.1955.02960320007003.
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Prior to World War II, the treatment of acute infectious hepatitis, or catarrhal jaundice as it was then frequently called, was the same as for other viral diseases: rest was prescribed during the acute phase but not enforced after the patient felt well and jaundice had begun to subside. During World War II, it was noted that relapses seemed to be associated with early ambulation, and, in addition, in three controlled studies1 it was shown that patients treated with a high-protein diet and strict bed rest had a shorter duration of hospitalization than those on a regimen of ad lib. rest and ad lib. diet. Emphasis was placed on an exercise tolerance test as a means of detecting harmful residual activity of the disease.2

As a result of these studies, there has been general agreement for the last 10 years that rest in bed should be strict and

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