During the phenomenal development of chemotherapy in the past thirteen years, considerable confusion has arisen regarding the value of the various agents in the management of acute septic peritonitis. Although most surgeons agree that chemotherapy has been of great value, there is no agreement as to which is the best agent to use or what is the best manner of its application. A summary of the present knowledge and experience is presented to establish the relative place of chemotherapy, the most effective agents and any changes in surgical practice made possible in the management of acute septic peritonitis.
There is still no specific treatment for acute septic peritonitis, and successful management is dependent primarily on good surgical intervention, aided by early and correct diagnosis, chemotherapy and adequate preoperative and postoperative care.
Early Correct Diagnosis.—
When peritonitis exists, the earlier the diagnosis is made, the more effective is prompt treatment. A