0
January 15, 1949, Vol 139, No. 3 >
ARTICLE | January 15, 1949

COMBINED STERPTOMYCIN-POTASSIUM IODIDE THERAPY

JAMA. 1949;139(3):158. doi:10.1001/jama.1949.02900200028014.
Text Size: A A A
Published online
Article
References

Iodides cause tubercle bacilli to appear in the sputum of patients with pulmonary tuberculosis. Jobling and Petersen1 showed that iodine neutralizes the fermentinhibiting properties of unsaturated fatty acids in caseous materials, thus releasing fermentation or autolysis. This causes a liberation of the bacilli and their appearance in the sputum. Jobling thought that the same autolytic process might serve a useful purpose by facilitating solution and absorption of caseous matter in other parts of the body and might thus expose masked tubercle bacilli to the influence of chemotherapeutic agents.

In the light of this significant suggestion and in view of the relatively poor results obtained in the treatment of fibrocaseous tuberculosis with streptomycin alone,2 Woody and Avery3 of the Department of Pathology, Vanderbilt University, tested the combined effect of potassium iodide and streptomycin against established tuberculosis in guinea pigs.

Forty-six young guinea pigs ranging in weight from 350

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Letters

Submit a Letter
CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Clear Answers | Save For Later
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs

More Listings at
JAMACareerCenter.com >

© 2013 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems