0
ARTICLE |

GLUTAMIC ACID AND INTELLIGENCE

JAMA. 1948;138(17):1231-1232. doi:10.1001/jama.1948.02900170025011.
Text Size: A A A
Published online

Experimental studies during the past twelve years have suggested that glutamic acid may bear some unique relation to the normal functioning of the brain. In 1936, the English worker Weil-Malherbe1 demonstrated that slices of the gray matter of rat and guinea pig brain will oxidize l-glutamic acid, the naturally occurring form, but would not oxidize the d-form, or any of twelve other amino acids studied. This investigation suggested that glutamic acid played some important part in brain metabolism, perhaps in the utilization of carbohydrate for energy. More recently it has been observed2 that l-glutamic acid increases formation of acetylcholine in extracts of rat brain, and still others have found that l-glutamic acid administered to rats enhances their ability to learn a simple maze3 and a somewhat more complicated problem box.4

Studies on the possible effect of glutamic acid in human subjects with

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();