0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Council on Pharmacy and Chemistry

JAMA. 1948;138(8):584-593. doi:10.1001/jama.1948.02900080042009.
Text Size: A A A
Published online

Extract

 The Effects of Streptomycin on Tuberculosis in Man, report to the Council on Pharmacy and Chemistry , J.A.M.A. 135:634-641 ( (Nov. 8) ) 1947
Link to Article[[XSLOpenURL/10.1001/jama.1947.02890100028007]]
The majority of these data were contributed by the following twenty-three hospitals. Fitzsimons General Hospital (USA), Denver; Corona Naval Hospital (USN), Corona, Calif., and Veterans Administration Hospitals at Brecksville, Ohio; Bronx, N. Y.; Butler, Pa.; Castle Point, N. Y.; Dayton, Ohio; Excelsior Springs, Mo.; Hines, Ill.; Legion, Texas; Livermore, Calif.; Memphis (Kennedy), Tenn.; Minneapolis; Oteen, N. C.; Richmond, Va.; Rutland Heights, Mass.; San Fernando, Calif.; Staten Island, N. Y.; Sunmount, N. Y.; Van Nuys, Calif.; Walla Walla, Wash.; Waukesha, Wis., and Wood, Wis. Data on a smaller number of cases were contributed by Veterans Administration Hospitals at Albuquerque, N. M.; Alexandria, La.; Bedford, Mass.; Chamblee, Ga.; Cleveland; Columbia, S. C.; Dearborn, Mich.; Fort Howard, Md.; Fort Logan, Colo.; Framingham, Mass.; Los Angeles; Louisville, Ky.; Martinsburg, W. Va.; McKinney, Texas; Nashville, Tenn.; Newington, Conn.; New Orleans; Oakland, Calif.; Outwood, Ky.; Springfield, Mo.; Temple, Texas; Wadsworth, Kan., and Whipple, Ariz., and by Nopeming Sanatorium, Nopeming, Minn., and Glen Lake Sanatorium, Oak Terrace, Minn.
 The Effect of Streptomycin upon Pulmonary Tuberculosis, Streptomycin Committee, Veterans Administration , Am. Rev. Tuberc. LVI: 485-605 ( (Dec.) ) 1947.
The results in 184 additional cases, from a single hospital, have been omitted because of differences in the method of study and reporting.
Dr. Howard M. Bosworth, Dr. William G. Childress, Dr. David A. Cooper, Dr. Bruce H. Douglas, Dr. H. Harold Fellows, Dr. John N. Hayes, Dr. Kirby S. Howlett Jr., Dr. Herbert L. Mantz, Dr. John H. Skawlem and Dr. Julius L. Wilson.
Brewer, L. A., III, and Bogen, E.;  Streptomycin in Tuberculous Tracheobronchitis , Am. Rev. Tuberc. LVI: 408-414 ( (Nov.) ) 1947.
Brock, B. L.:  Streptomycin in the Treatment of Draining Tuberculous Sinuses , J. A. M. A. 135:147-149 ( (Sept. 20) ) 1947.
Link to Article[[XSLOpenURL/10.1001/jama.1947.02890030015005]]
Bunn, P. A.:  One Hundred Cases of Miliary and Meningeal Tuberculosis Treated with Streptomycin , Am. J. M. Sc. , to be published.
Conducted on March 6 and 7, 1948, by Dr. Ralph K. Ghormley of the Mayo Clinic and Prof. Edward Evans of the University of Minnesota and their staffs.
Mason, E. E., and others:  Streptomycin in the Treatment of Tuberculous Enteritis , Am. J. M. Sc. , to be published.
Farrington, R. F.: Hull-Smith, H.; Bunn, P. A., and McDermott, W.:  Streptomycin Toxicity , J. A. M. A. 134:679-688 ( (June 21) ) 1947.
Link to Article[[XSLOpenURL/10.1001/jama.1947.02880250027007]]
This figure is rather arbitrarily selected as a criterion of resistance since it represents the average blood concentration from four to six hours after the intramuscular injection of 0.5 Gm. of streptomycin. since
Steenken, W., Jr.: Resistance: Minutes of the Fourth Streptomycin Conference , St. Louis, Veterans Administration, (May 1) , 2 and 3, 1947, pp. 52-56.
Feldman, W. H.; Karlson, A. G., and Hinshaw, H. C.:  Streptomycin Resistant Tubercle Bacilli: Effects of Resistance on Therapeutic Results in Tuberculous Guinea Pigs , Am. Rev. Tuberc. LVII: 162-174 ( (Feb.) ) 1948.
Figure 8 represents an attempt to indicate, graphically, the relative therapeutic effectiveness of streptomycin in various types of tuberculosis. The criteria selected for evaluation of effectiveness are mentioned in each instance, but it should be emphasized that any change in these criteria would decidedly alter both the height and the shading of the individual columns; thus, the acceptance of roentgenologic improvement instead of sputum conversion would increase the "pulmonary" column from 25 to 80 per cent and the inclusion of a post-treatment observation period would nearly double the height of the "bone and joint" column. Its information, therefore, is general rather than specific; its usefulness is qualitative rather than quantitative.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();