LOCAL INJECTION OF HYDROCORTISONE TERTIARY-BUTYLACETATE IN SKIN LESIONS

To the Editor:—  In spite of the efficacy of topical applications of ointments and lotions of corticosteroids in certain common skin conditions, such as infantile eczema, atopic dermatitis, pruritus ani, and mild contact dermatitis, direct intralesional injections are still necessary and practical in treating lesions that do not respond readily to topical applications. In this list are small patches of psoriasis, especially on exposed areas; small patches of discoid lupus erythematosus, still persistent after systemic therapy with chloroquine or chlorochloroquine; keloids; localized myxedema; localized scleroderma; granuloma annulare; and small areas of leukemic lesions or other specific cutaneous lesions of the lymphomas. A second group of lesions for which injections may be used includes those that may respond in part to topical applications, especially small areas of the deep lesions of localized neurodermatitis.We have used suspensions of hydrocortisone acetate and alcohol with an ordinary syringe and needle, also in the