This is an attempt to present the new and practical methods of therapeutics in the form of an alphabetic card index. Technics, dosage and methodology of treatment with the newer drugs are given in summary form, and many of the cards carry ready references to recent literature for more details. It is the stated intention of the authors to evolve a system that shall become increasingly comprehensive. For this purpose constructive criticism of subscribers has been requested. When fully developed, the card index guide should offer a useful and ready reference for the busy practitioner, particularly if it is kept up to date by frequent review of the newer developments in treatment.