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SPORADIC ACUTE ANICTERIC HEPATITIS ASSOCIATED WITH UPPER RESPIRATORY INFECTION

Robert L. Chancey; Leslie M. Zatz, (MC)
JAMA. 1955;158(12):1013-1016. doi:10.1001/jama.1955.02960120013005.
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Anicteric hepatitis occurring in the absence of epidemics of infectious hepatitis has been infrequently reported in the English language literature. Only three references have been located pertaining specifically to this condition in the past 15 years.1 During the first seven months of 1954, 43 cases of anicteric hepatitis associated with upper respiratory infections were observed and treated. These cases occurred sporadically in young men at an Air Force base in Colorado. This illness deserves emphasis because of its unusual nature and the possibility of chronic sequelae if it is unrecognized. In the 43 cases observed, the age range of the men was from 17 to 32; a large majority were in the age group 17 to 22, as would be expected in a military population. Anicteric hepatitis was first encountered in these men in January, 1954, and sporadic cases have continued to appear to the time of this writing.

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