JAMA. 1948;137(13):1132. doi:10.1001/jama.1948.02890470032009.
Text Size: A A A
Published online

Not many years have passed since one took for granted that the human fetus is optimally protected and maintained in utero. Attempts were not made to influence the environment of the fetus, because whatever abnormalities developed were believed to be due either to intrinsic causes or, in a smaller number of instances, to extrinsic factors beyond comprehension or control. Syphilis was one of the few exceptions to this rule.

As has happened previously when a subject was ripe for exploration, numerous lines of research are now converging, as if by accident, on pathologic conditions of the fetus. Much valuable information has been acquired; now new and old knowledge can be assembled into a systematic scientific structure.1 The field includes two mutually related parts, namely, abnormalities of development and diseases of the fetus.

Some recent advances from clinical studies are of immediate significance to the practicing physician:


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.