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JAMA. 1948;137(12):1042. doi:10.1001/jama.1948.02890460038009.
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Experimental and clinical observations have demonstrated the existence of cortical representation of autonomic function and of abdominal sensations produced by cortical stimulation. Watts and Fulton1 produced experimental diencephalic lesions which resulted in disturbed gastrointestinal activity. The probable role of the diencephalon in the production of peptic ulcer following brain trauma was emphasized by Cushing. Penfield and Gage2 exposed the brain of a patient under local anesthesia and stimulated electrically an area just posterior to the postcentral convolution. The patient complained of a pain in the right abdominal quadrant like that experienced before her epileptic attacks. Faradic stimulation in front of this area reproduced what for her was a typical seizure. Winkelman3 cited the case of a man who experienced intense abdominal pain as the initial symptom of a cerebral hemorrhage involving the frontoparietal area. Klingman4 and his co-workers reported observations on 12 children with paroxysmal attacks


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