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REDUCTION OF INFECTIVITY OF CERTAIN PATHOGENIC BACTERIA BY "MERCUROCHROME"

JOHN H. BREWER, Ph. D.
JAMA. 1948;137(10):858-861. doi:10.1001/jama.1948.82890440002008.
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In a recent report the Council on Pharmacy and Chemistry of the American Medical Association, commenting on the article, " Bacteriostatic and Bactericidal Actions of Some Mercurial Compounds on Hemolytic Streptococci" by Morton, North and Engley,1 expresses deep concern as to the value and usefulness of certain mercurial antiseptics, including " mercurochrome" (merbromin N.F.). As a matter of fact, a challenge was made to the manufacturers of mercurial antiseptics in the statement that this " is a field in which, wishful thinking is dangerous," and experimental verification of the usefulness of the products was requested. It seems that the Council is mainly impressed by these observations which presume to show that the infectivity of hemolytic streptococci has not been impaired by treatment with mercurial antiseptics. In reply my associates and I submit laboratory data which answer this question and others raised by the Council.

Although the technic described in this report does

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