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William H. Perloff, M.D.
JAMA. 1955;157(8):651-652. doi:10.1001/jama.1955.02950250025006.
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This report consists of a description of four hypothyroid children, one male and three females, who had an unusual type of hirsutism (fig. 1) that disappeared within six to eight months after the initiation of treatment with desiccated thyroid.


Case 1.—  A 2 1/2-year-old white girl who had the chief complaint of marked hirsutism was described by her mother as being very sluggish, and there was nothing in the history to suggest abnormality of development or growth. Except for the hirsutism, which had been present since birth, there were no other complaints. The patient's height was 37 in. (94 cm.), and her weight was 35 lb. (16 kg.). The skin was dry, and the head hair was coarse and dry. Her complexion was pallid, and marked protrusion of the abdomen was present, but this was due, at least in part, to lordosis of the spine. Of particular


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