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ROLE OF HEREDITY IN THE PROBLEM OF HYPERTENSION IN INDUSTRIAL WORKERS

Constance A. D'Alonzo, M.D.; Allan J. Fleming, M.D.; George H. Gehrmann, M.D.
JAMA. 1955;157(8):631-633. doi:10.1001/jama.1955.02950250005002.
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The exact role of heredity in hypertension has not been evaluated satisfactorily. Page1 has said: "Perhaps much of the diversity of opinion regarding the importance of heredity in hypertension is due to lack of care in defining what is meant by a 'positive family history.' " He believes that the family history is positive in most cases of essential hypertension and quotes a penetrating analysis of the problem by Platt: "Briefly stated, his data, which should be extended, is in accord with the view that essential hypertension is a dominant trait. A positive family history in a patient with hypertension suggests, with a 6:1 probability, that the process is essential. A negative family history indicates with only 3:1 probability that the hypertension is secondary, due most often to renal disease." It would appear, therefore, that when there is a positive family history it is more likely that a case of

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