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TREATMENT OF TUBERCULOUS ULCER OF THE TONGUE WITH STREPTOMYCIN

HENRY WOLFER, M.D.; IRVING HIRSHLEIFER, M.D.; RAYMOND SHAPIRO, D.D.S., M.D.
JAMA. 1948;136(4):249-250. doi:10.1001/jama.1948.72890210006006.
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Lingual tuberculosis is not frequent.1 Up to 1945 there were only slightly more than 400 reported cases,2 of which the largest number were found in patients over 40 years of age. Of this group a preponderance were found in the fifth decade.1b Males are more often affected than females, and Negroes infrequently. The infrequency of tuberculous ulcers of the tongue may be due to the vascularity of the organ, constant mechanical action of the tongue, possible germicidal action of the glandular secretions,1a and the general resistance of striated muscle to bacterial invasion.2

Tuberculosis of the tongue is caused by the lodgment of tubercle bacilli in the tissue of the tongue and their subsequent proliferation. Theoretically the bacilli may reach the tongue by hematogenous spread, lymphatic spread, direct extension or actual contact. Primary tuberculosis of the tongue if existing is rare.1a It is usually secondary to

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