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George T. Harrell, M.D.
JAMA. 1947;135(11):732. doi:10.1001/jama.1947.02890110050020.
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To the Editor:—  Some facts have been accumulated in the United States which bear on the discussions of the epidemiology of leprosy which have appeared in The Journal (Oct. 19, 1946, p. 407; Dec. 14, 1946, p. 947; Aug. 9, 1947, p. 1261).The possibility that generalized sarcoidosis of Boeck may be caused in some instances by Mycobacterium leprae had been suggested by the clinical and pathologic resemblance of certain cases of sarcoid to tuberculoid leprosy. The results of lepromin (Mitsuda) tests in sarcoid were reported in the American Journal of Tropical Medicine (25:523-535 [Nov.] 1945). North Carolina is an area where leprosy is not endemic—at least, clinical cases are not recognized; cases of sarcoid are seen in adults with some frequency. No case of sarcoid under study in North Carolina has later been diagnosed as leprosy; the experience in Louisiana and Texas may be different. Sarcoid is an


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