Howard W. Mahaffey, M.D.
JAMA. 1954;156(4):312-313. doi:10.1001/jama.1954.02950040018005a.
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The intra-articular use of hydrocortisone for the relief of arthritic pain has been well established. Hollander ' has reported the injection of 7,352 joints with adverse reactions in 2.3%, of which in 1.9% the adverse reaction was local exacerbation of pain. Intra-articular hydrocortisone is useful in relieving the pain of arthritis, either rheumatoid or osteoarthritic, and the reaction of joints following trauma, surgery, and gout. The knee joint is commonly the site of involvement of arthritic changes and, at this clinic, has been injected more often than any other joint. The method of injection that has been used for the past 18 months has greatly simplified this therapy and has eliminated much of the discomfort associated with inserting a needle into the knee joint.

The patient is placed in a sitting position with the knees flexed to an angle of 90 degrees. The patella and infrapatellar ligament are identified (fig.


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