JAMA. 1947;135(2):90. doi:10.1001/jama.1947.62890020002007a.
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In the use of epinephrine in cardiac resuscitation evidence is at hand to show that the effective stimulus is not always the needle prick of the heart wall, as has often been asserted but that the epinephrine itself is important. It may be well to mention also the frequency with which dangerous doses of this agent are used.

The technics of cardiac resuscitation continue to offer much material for debate. Arguments for or against the importance of a given practice have not yet been settled by direct observation in man in many instances. In cases in which it is possible to make direct observations it is important to report the evidence.

REPORT OF CASE  The following case illustrates that the needle prick and massage were not adequate to revive a heart that had failed. The injection of epinephrine and massage of the heart proved adequate on two occasions.A girl


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