0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

ENGLAND

JAMA. 1954;155(9):855-857. doi:10.1001/jama.1954.03690270051024.
Text Size: A A A
Published online

ABSTRACT

Penicillin.  —Two recent reports indicate the growing interest in penicillin for oral use, especially in children. Fairbrother and Daber (Lancet1:858, 1954) compare the insoluble benzathine penicillin (Penidural) with the soluble potassium penicillin G (Eskacillin) and the potassium salt of benzylpenicillin (Pradupen). A single dose of 300,000 to 600,000 units of benzathine penicillin was given to 181 patients (150 adults and 31 children). In adults, a dose of 300,000 units "gave disappointing results and was discontinued." With a dose of 600,000 units, a detectable serum penicillin level was found within three hours in 67 of 68 assays, and in six patients a level of 0.5 unit or more per milliliter was obtained. After five or six hours, 37 of 59 persons still had levels of 0.06 unit or more per milliliter. The results in children were more satisfactory. All had detectable serum-penicillin levels after a dose of 300,000 units;

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();