0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

THE PATHOLOGY OF EPIDEMIC HEPATITIS

TRACY B. MALLORY
JAMA. 1947;134(8):655-662. doi:10.1001/jama.1947.02880250003002.
Text Size: A A A
Published online

In the present state of knowledge of epidemic hepatitis, this disease can be defined only in descriptive terms, since the infectious agent has not yet been isolated and identified. The disease is transmissible to human beings by oral or parenteral inoculation with a filter-passing agent, presumably a virus,1 but in contrast to spirochetal jaundice and yellow fever experimental infection of animals has never been accomplished. It is characterized clinically by evidence of hepatic dysfunction and pathologically by inflammatory and degenerative changes in the hepatic parenchyma. It ordinarily runs a benign, self-limited course of two to three weeks' duration, but symptoms may persist for months, with or without acute recrudescences. Although the mortality is low, death may occur at any stage. On clinical and pathologic grounds it is indistinguishable from the endemic, sporadic disease known for many years as catarrhal jaundice, from homologous serum jaundice and from at least certain

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();