September 30, 1939, Vol 113, No. 14 >

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HYPOTHYROIDISM IN THE CAUSATION OF ABORTION, ESPECIALLY OF THE "MISSED" VARIETY

E. L. KING; J. S. HERRING, M.D.

JAMA. 1939;113(14):1300-1302. doi:10.1001/jama.1939.02800390022006.

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Whether we are entirely correct in applying the term "hypothyroidism" in each of the cases under consideration might be questioned, as the diagnosis is based chiefly on the determination of the basal metabolic rate. However, as we are concerned particularly with early pregnancy, in which indefinite manifestations such as malaise and fatigability are so common, we find that we are not in a position to base our diagnosis on the usual symptoms of hypothyroidism. It is our opinion, moreover, that the minor degrees of this state may be practically symptomless and yet may seriously affect the reproductive function. This is in accord with the views of Litzenberg and Carey,¹ who stated that "it would seem apparent that any deviation from the normal rate must be due to thyroid influence and inasmuch as the patient usually responds to thyroid medication we have used the term 'hypothyroidism' in spite of the

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KING EL, HERRING JS. HYPOTHYROIDISM IN THE CAUSATION OF ABORTION, ESPECIALLY OF THE "MISSED" VARIETY. JAMA. 1939;113(14):1300-1302. doi:10.1001/jama.1939.02800390022006.

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