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September 16, 1939, Vol 113, No. 12 >

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Other Articles | September 16, 1939

INFLUENZAL MENINGITIS WITH BACTEREMIA TREATED WITH SULFAPYRIDINE: RECOVERY

Tom R. Hamilton, M.D.; Frank C. Neff, M.D.
JAMA. 1939;113(12):1123-1125. doi:10.1001/jama.1939.72800370001010.
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During the period of clinical trial of Dagenan1 at the University of Kansas Hospitals a 2 year old girl with meningitis was sent into the children's department by the family physician2 for assistance in identifying the type of organisms which he had found in the spinal fluid. With a cell count of 5,000 per cubic millimeter and many organisms visible on the stained slide, the physician found it difficult to identify the various forms which were present but thought that they might be pneumococci and hoped that they might be amenable to serum treatment. We report the case with the rationale of the diagnosis and its treatment with sulfapyridine. In the absence of any known specific therapy we had hoped that this drug might be effective in what we found to be influenzal meningitis with bacteremia.

REPORT OF CASE  Phyllis B., aged 2 years, was observed by the

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