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R. S. Gilfillan, M.D.; O. W. Jones Jr., M.D.; S. I. Roland, M.D.; E. J. Wylie, M.D.
JAMA. 1954;154(14):1149-1152. doi:10.1001/jama.1954.02940480001001.
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The veterinarian Boullay first described the syndrome of intermittent claudication as early as 1831.1 In 1858, Jean Marie Charcot described lameness and pain of claudication in horses pulling carriages. His description of a patient with an aneurysm of the common iliac artery was the first that gave an accurate and comprehensive survey of the clinical picture of pain due to vascular insufficiency in the lower extremity of man.2 Failure of circulation to specific muscle groups and the appearance of sensory changes during exercise are only of relatively recent recognition. Where unusual types of claudication and ischemic hypesthesia appear, they are often confused with neurological syndromes. It is the purpose of this paper to describe several types of pain and sensory changes arising in arterial disease of the lower extremity that manifest a strong resemblance to primary neurological disease and to present illustrative case histories.



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