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JAMA. 1947;133(14):994-998. doi:10.1001/jama.1947.02880140024005.
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In any general discussion of intestinal tumors it is proper that principal attention be paid to the malignant neoplasms, which constitute the majority of such tumors. Almost all of these are confined to the colon, arising from tissue of ectodermal origin. It is common knowledge that such malignant tumors may arise in the small intestine as well, although these are rare. Benign tumors of ectodermal origin, such as polyps, are again common in the colon and rare in the small intestine. Malignant neoplasms of mesodermal origin are far fewer than carcinomas and are about equally frequent in small and large intestine. Benign mesodermal tumors are rare and seem to have a predilection for the upper and lower ends of the small intestine.

Although inflammatory intestinal tumors have not been recognized with any frequency until recent years, Virchow1 as early as 1853 described inflammatory tumors or "pseudotumors" of the bowel,


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