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ARTICLE |

MACROSCOPIC DIAGNOSIS IN LIVER BIOPSY

Richard B. Terry, M.D.
JAMA. 1954;154(12):990-992. doi:10.1001/jama.1954.02940460022006c.
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Although the macroscopic features of the specimens obtained by needle biopsy of the liver are often informative and helpful in diagnosis, they have been disregarded largely because the specimens obtained by the usual techniques are unsuitable for naked-eye examination. This report deals (a) with a method of obtaining, by biopsy, specimens of the liver of adequate size and in suitable condition for macroscopic examination and (b) with the gross appearance of such specimens in various disorders.

The Vim-Silverman needle, which is generally preferred in America, is simple to use. However, the specimen is taken by a split inner needle with a bore of less than 1 mm. that projects only 2 cm. beyond the bevel of the outer needle. The specimen is therefore small, with a maximum volume of about 12.5 cu. mm. It is difficult to prepare for naked-eye examination since it is held inside the split needle, and

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