This book is essentially an electron microscopist's vade mecum, written by a master craftsman in the fine art of electron microscopy. Its primary preoccupation is with instrumentation, technical procedure and the myriad areas of application which have already emerged in this teen-aged craft of the visualization of ultramicroscopic structure. The illustrations are rich, varied and technically superb; they are undoubtedly the finest collection of pictures that have thus far been published to exhibit the applications of electron microscopy. The book is a highly individualized account of the wide experience of the author and his laboratory. As such it has the freshness and authenticity of personal experience; it suffers for the same reason from the limitations of the author's personal preferences and from inadequate assimilation and presentation of the work of other investigators of the biophysics and biochemistry of ultrastructure.
Successive chapters describe electron microscopes themselves; adjustment and operation; preparative procedures