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Robert M. Zollinger, M.D.; Edwin H. Ellison, M.D.
JAMA. 1954;154(10):811-814. doi:10.1001/jama.1954.02940440009002.
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A significant number of gastric operations result in rather distressing postoperative complaints that are unrelated to the original pathology and probably are referable to the surgical procedure.1 Although the loss of a part or all of the stomach may seem a small price to pay to avoid the consequences of recurrent ulcer or fatal neoplasm, a significant number of patients manifest subsequent nutritional deficiencies that may be severe enough to prove incapacitating to the occasional patient.2 During the past three and one-half years a study has been undertaken in an attempt to gain further information regarding the incidence, etiology, management, and possibly the prevention of nutritional problems following gastric surgery.

Physicians responsible for the late postoperative care of patients with gastric surgery have long been impressed by the problems they present. Diminished appetite, limited food capacity, frequent discomfort after meals, high incidence of food idiosyncrasy, and occasional diarrhea


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